SEATTLE (AP) — Colorado coach Tad Boyle didn't have any final diagnosis to give about Spencer Dinwiddie's injured left knee.

His gut feeling told him the 15th-ranked Buffaloes better prepare for him not being around.

"My gut is not good. But we'll see. If he's out, he's out. I just feel so bad for the kid because he's worked so hard," Boyle said after Sunday's 71-54 loss to Washington. "We obviously missed him in the second half and he means a lot for our team. If he is out we have to figure some things out and learn how to overcome. It was a blow no doubt."

C.J. Wilcox set career highs with seven 3-pointers and 31 points, including 21 in the second half, for the Huskies.

It was Washington's first win over a ranked team since Isaiah Thomas' jumper beat then-No. 16 Arizona in the 2011 Pac-10 Conference tournament championship game. Washington (11-6, 3-1 Pac-12) had lost 12 straight against ranked teams.

"When he gets in a zone he's pretty special that way," Washington coach Lorenzo Romar said of Wilcox.

The Buffaloes (14-3, 3-1) were without their star for the final 23 minutes after Dinwiddie went down late in the first half. He crumpled to the court late in the first half after his left knee buckled while dribbling on a fast break. Dinwiddie had to be helped to the locker room by teammates and did not return.

The Huskies outscored the Buffaloes 49-29 after Dinwiddie's injury. He's expected to be examined on Monday in Boulder.

"It's hard on them. There is no question it's hard. Emotion is a big part of this game, any game at this level, so we'll find out where he is at but it was definitely an emotional blow to our team," Boyle said. "I thought we finished the first half well, I don't know if we were going on fumes or what, but we shot ourselves in the foot. You turn the ball over 20 times against a good team and you've got six assists, it's a recipe for disaster."

Colorado was trying for the second-best start in school history, but fell short after being pushed to overtime by Washington State on Wednesday night.

Dinwiddie crumpled to the court after taking an awkward step on a fast break and his left knee buckled. He was on the court for a few minutes while trainers and Boyle came on to his side. Dinwiddie was helped to his feet but had to be assisted off the court with his arms around teammates.

Dinwiddie, who had seven points in 15 minutes, was chastised by Boyle after scoring a disappointing six points in 38 minutes on Wednesday night.

"He's the leader of our team. It was a big loss but that's not a reason for how we lost that game," said Josh Scott, who led Colorado with 15 points. "We didn't do what we needed to do."

Colorado's Askia Booker, the reigning Pac-12 player of the week, was 0 for 9 from the field and went scoreless for just the second time in his college career. The last time Booker failed to score was late in his freshman season against Arizona.

The Buffaloes had no answer for Wilcox's shooting in the final 20 minutes. Washington started the second half on a 12-5 run thanks to three 3-pointers from Wilcox. The complexion of the second half could have changed when Perris Blackwell, the Huskies' only true inside presence, picked up his fourth foul with 15:52 remaining.

Scott tried to stem the run with five straight points for the Buffaloes but Wilcox continued to knock down shots. He hit another 3 when Nigel Williams-Goss broke the Colorado press and found him open in front of the Washington bench. He scored off a steal with a left-handed layup and hit another stand-still 3 for a 51-39 lead, his sixth straight make to start the second half.

Andrew Andrews added a driving layup to push the lead to 14 before Scott finally scored in the lane to briefly stop the run. Washington went up 18 when Wilcox knocked down his seventh 3-pointer with 6:42 left for a 61-43 lead.

Andrews added 14 points for Washington and Williams-Goss had 12.